OR28-03 Drug Repurposing Identifies Inhibitors of the Proteostasis Network to Augment Radioiodine Uptake in Combinatorial Approaches Targeting Thyroid Cancer

New combinatorial drug strategies are urgently needed to improve radioiodine (RAI) uptake and efficiently ablate thyroid cancer cells, thereby reducing the risk of recurrent disease. Drug repurposing offers the promise of identifying already approved compounds capable of inducing sodium iodide sympo...

Descripción completa

Detalles Bibliográficos
Autores principales: Read, Martin L, Brookes, Katie, Fletcher, Alice, Thornton, Caitlin E M, Alshahrani, Mohammed, Khan, Rashida, Nieto, Hannah R, Adcock, Holly V, Webster, Jamie R M, Cox, Liam, Alderwick, Luke J, Boelaert, Kristien, Smith, Vicki E, McCabe, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Thyroid
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208217/
http://dx.doi.org/10.1210/jendso/bvaa046.2135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208217/
http://dx.doi.org/10.1210/jendso/bvaa046.2135

Ejemplares similares