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SAT-742 Characterising the Metabolism, Glucuronidation and Sulfation of C11-oxy C(19) Steroids
The metabolism of 11β-hydroxyandrostenedione (11OHA4), a major adrenal C(19) steroid, was first characterised in our in vitro prostate models showing that 11OHA4, catalysed by 11βHSDs, 17βHSDs and 5α-reductases, yields potent androgens, 11keto-testosterone (11KT) and 11keto-dihydrotestosterone (11KD...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208218/ http://dx.doi.org/10.1210/jendso/bvaa046.792 |