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MON-290 Ipilimumab Immune-Related ACTH Deficiency Is of Acute Onset and Severe

Introduction Immune checkpoint inhibitors (ICIs) are immunomodulatory molecules that downregulate T-cell inhibiting-receptors or ligands to promote an enhanced anti-tumour response. Ipilimumab is a human monoclonal antibody directed against cytotoxic T-lymphocyte antigen-4 (CTLA-4) that has been sho...

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Detalles Bibliográficos
Autores principales: Seejore, Khyatisha, Giannoudi, Marilena, Osborn, Djoah, Lynch, Julie Marie, Dunwoodie, Elaine, Hook, Jane, Marples, Maria, Murray, Robert Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208295/
http://dx.doi.org/10.1210/jendso/bvaa046.1486