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OR24-02 Identification of Membrane Proteins That Enhance the Responsiveness of the Ghrelin Receptor

Ghrelin, a 28-amino acid peptide gut hormone, occurs in acylated (AG) and unacylated (UAG) variants. AG is a GH secretagogue as well as being orexigenic and diabetogenic, acting via the growth hormone secretagogue receptor (GHSR1a) in the hypothalamus and pituitary. UAG counteracts these metabolic e...

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Detalles Bibliográficos
Autores principales: Prins, Karina, Visser, Jenny A, Huisman, Martin, Mies, Rosinda, Neggers, Sebastian J C M M, der Lely, Aart Jan Van, Delhanty, Patric J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208365/
http://dx.doi.org/10.1210/jendso/bvaa046.1654