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SAT-LB72 Design of the PaTH Forward Phase 2 Trial of TransCon PTH, a Long-Acting PTH, in Patients With Hypoparathyroidism

Background: Hypoparathyroidism (HP) is caused by a deficiency in parathyroid hormone (PTH), which leads to hypocalcemia and hyperphosphatemia. Standard of care (SoC), i.e. large doses of calcium (Ca) and active vitamin D, worsens hypercalciuria and increases the serum Ca (sCa) x serum phosphate (sP)...

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Detalles Bibliográficos
Autores principales: Khan, Aliya Aziz, Rejnmark, Lars, Schwarz, Peter E, Vokes, Tamara J, Clarke, Bart Lyman, Rubin, Mishaela Ruth, Hofbauer, Lorenz C, Erikson, Erik, Palermo, Andrea, Pagotto, Uberto, Marcocci, Claudio, Ahmed, Intekhab, Mourya, Sanchita, Markova, Denka, Karpf, David B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208407/
http://dx.doi.org/10.1210/jendso/bvaa046.2209