OR26-01 Epinephrine Is Essential for Normal Renal Glucose Reabsorption via the Glucose Transporter GLUT2

Humans and mice with Melanocortin 4 receptor (MC4R) deficiency remain protected from hyperglycemia despite chronic obesity and insulin resistance. We have observed that elevated glycosuria in MC4R deficient mice protects them from hyperglycemia. Moreover, our results indicate that circulating epinep...

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Detalles Bibliográficos
Autores principales: Elsheikh, Arwa Mahmoud, de Souza Cordeiro, Leticia M, Devisetty, Nagavardhini, Ebert, Steven N, Chhabra, Kavaljit H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208471/
http://dx.doi.org/10.1210/jendso/bvaa046.524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208471/
http://dx.doi.org/10.1210/jendso/bvaa046.524

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