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OR26-01 Epinephrine Is Essential for Normal Renal Glucose Reabsorption via the Glucose Transporter GLUT2
Humans and mice with Melanocortin 4 receptor (MC4R) deficiency remain protected from hyperglycemia despite chronic obesity and insulin resistance. We have observed that elevated glycosuria in MC4R deficient mice protects them from hyperglycemia. Moreover, our results indicate that circulating epinep...
Autores principales: | Elsheikh, Arwa Mahmoud, de Souza Cordeiro, Leticia M, Devisetty, Nagavardhini, Ebert, Steven N, Chhabra, Kavaljit H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208471/ http://dx.doi.org/10.1210/jendso/bvaa046.524 |
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