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SUN-LB40 Chronic Cortisol Works Through the Transcription Factor KLF9 to Deregulate Immune Response and Metabolism

Chronically elevated levels of glucocorticoids (GC) are associated with a number of disease states and negative side effects, including metabolic syndrome. Epidemiological studies show that elevated GC during a brief but vulnerable developmental window can have life-long and potentially multi-genera...

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Detalles Bibliográficos
Autores principales: Gans, Ian M, Hartig, Ellen I, Tilden, Andrea R, Graber, Joel H, Coffman, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208612/
http://dx.doi.org/10.1210/jendso/bvaa046.2322