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SUN-214 A Novel Glucocorticoid Receptor Antagonist (CORT113176) Reveals Unique Developmental and Tissue-Specific Effects in a Neonatal Rat Model of Human Prematurity

Premature birth is a major public health problem worldwide and can lead to transient adrenal insufficiency(1,2). The stress of premature birth includes the inability to control blood glucose and maintain normal oxygenation leading to hypoxia(3). Corticosteroid administration enhances surfactant prod...

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Detalles Bibliográficos
Autores principales: Welhouse, Kyle D, Gehrand, Ashley, Phillips, Jonathan, Siddiqui, Hana, Schulgit, Matthew, Raff, Hershel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208664/
http://dx.doi.org/10.1210/jendso/bvaa046.321