Cargando…
SUN-214 A Novel Glucocorticoid Receptor Antagonist (CORT113176) Reveals Unique Developmental and Tissue-Specific Effects in a Neonatal Rat Model of Human Prematurity
Premature birth is a major public health problem worldwide and can lead to transient adrenal insufficiency(1,2). The stress of premature birth includes the inability to control blood glucose and maintain normal oxygenation leading to hypoxia(3). Corticosteroid administration enhances surfactant prod...
Autores principales: | Welhouse, Kyle D, Gehrand, Ashley, Phillips, Jonathan, Siddiqui, Hana, Schulgit, Matthew, Raff, Hershel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208664/ http://dx.doi.org/10.1210/jendso/bvaa046.321 |
Ejemplares similares
-
The Effect of a Novel Glucocorticoid Receptor Antagonist (CORT113176) on Glucocorticoid and Insulin Receptor Sensitive Hepatic Gene (mRNA) Expression in a Neonatal Rat Model of Human Prematurity
por: Gehrand, Ashley, et al.
Publicado: (2021) -
SUN-400 Assay-Specific Spurious ACTH Results Lead to Misdiagnosis, Unnecessary Testing, and Surgical Misadventure: A Case Series
por: Greene, Loren, et al.
Publicado: (2019) -
MON-172 Comparison of a Late-night Salivary Cortisol Immunoassay and a Cortisol and Cortisone LCMS Assay in Patients with Cushing’s Disease
por: Kannankeril, Joshua, et al.
Publicado: (2020) -
SUN-207 Modelling Long Term Glucocorticoid-Induced HPA Axis Suppression in Mice
por: Romano, Nicola, et al.
Publicado: (2020) -
SUN-217 Skin Glucocorticoid Metabolism in Burn Injury: Towards Novel Treatments That Reduce Scarring
por: Tsai, Kevin Hung-Yueh, et al.
Publicado: (2020)