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SAT-396 A Non-Surgical Animal Model of Hypoparathyroidism for Testing PTH Analogues

BACKGROUND: In vivo animal models for testing the pharmacokinetics and bioactivity of PTH and its analogues require parathyroidectomy by surgery (1, 2). As the parathyroid glands of rodents are very small the surgery often includes thyroidectomy, making this animal model time-limited, single use, co...

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Detalles Bibliográficos
Autores principales: Ramezani-Pour, Narjes, Esfahani, Sayyed Hamid Zarkesh, Pradhananga, Sarbendra, Newell-Price, John D C, Ross, Richard John M, Wilkinson, Ian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208699/
http://dx.doi.org/10.1210/jendso/bvaa046.505