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SUN-LB138 Dynamic Structural Model of Testosterone Entry Into the Unliganded Androgen Receptor

Background: Crystallographic structures of nuclear receptor ligand binding domains provide a static model of a receptor stably wrapped around an internalized ligand. Understanding the dynamics of a receptor at different stages of ligand binding has been hampered by the paucity of crystal structures...

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Detalles Bibliográficos
Autores principales: Krylova, Irina, Schaufele, Fred J, Guilbert, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208788/
http://dx.doi.org/10.1210/jendso/bvaa046.2079