SUN-LB118 Mice With Skeletal Muscle-Specific DRP1 Deficiency Are Resistant to Obesity and Diabetes Induced by a High Fat Diet

The skeletal muscle of type 2 diabetics exhibits mitochondrial dysfunction associated with increased mitochondrial fission. Dynamin-related protein 1 (DRP1) is responsible for mitochondrial division, whereas mitochondrial-endoplasmic reticulum contacts (MERCs) mark mitochondrial sites where fission...

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Detalles Bibliográficos
Autores principales: Jensen, Renato Daniel, Peterson, Joshua, Allington, Benjamin, Dieter, Alayna, Cheng, Linhai, Soto, Jamie, Alambert, Renata Pereira, Correia, Marcelo, Abel, Evan Dale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208802/
http://dx.doi.org/10.1210/jendso/bvaa046.2320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208802/
http://dx.doi.org/10.1210/jendso/bvaa046.2320

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