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SAT-LB138 The LncRNA Growth Arrest Specific 5 Regulates Cell Survival via Distinct Structural Modules With Independent Functions

The growth arrest-specific 5 (gas5) gene encodes a long non-coding RNA (lncRNA) that is required for normal growth arrest, slows down the cell cycle, controls apoptosis, and is required for the inhibition of cell growth by mTOR inhibitors such as rapamycin. In agreement with this role in regulating...

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Detalles Bibliográficos
Autores principales: Frank, Filipp, Kavousi, Nadieh, Bountali, Aikaterina, Dammer, Eric, Mourtada-Maarabouni, Mirna, Ortlund, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208830/
http://dx.doi.org/10.1210/jendso/bvaa046.2327