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SAT-LB138 The LncRNA Growth Arrest Specific 5 Regulates Cell Survival via Distinct Structural Modules With Independent Functions
The growth arrest-specific 5 (gas5) gene encodes a long non-coding RNA (lncRNA) that is required for normal growth arrest, slows down the cell cycle, controls apoptosis, and is required for the inhibition of cell growth by mTOR inhibitors such as rapamycin. In agreement with this role in regulating...
Autores principales: | Frank, Filipp, Kavousi, Nadieh, Bountali, Aikaterina, Dammer, Eric, Mourtada-Maarabouni, Mirna, Ortlund, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208830/ http://dx.doi.org/10.1210/jendso/bvaa046.2327 |
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