OR12-03 Mineralocorticoid and Glucocorticoid Receptors Adopt Distinct Quaternary Structures and Can Form Heteromultimers That Affect Chromatin-Binding Profiles

The mineralocorticoid and glucocorticoid receptors (MR and GR) are evolutionarily related nuclear receptors with high sequence conservation and a shared hormone response element (HRE). Both receptors are activated by glucocorticoids, but MR can be selectively activated by aldosterone. Using the imag...

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Detalles Bibliográficos
Autores principales: de la Rosa, Diego Alvarez, Johnson, Thomas A, Fettweis, Gregory, Hager, Gordon L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Steroid Hormones and Receptors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209005/
http://dx.doi.org/10.1210/jendso/bvaa046.1651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209005/
http://dx.doi.org/10.1210/jendso/bvaa046.1651

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