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SAT-LB26 A Dual Role for IGF-1R in Mammary Tumorigenesis

The insulin-like growth factor type 1 receptor (IGF-1R) is now thought to have a dual function in breast cancer. Several studies have shown overexpression of the IGF-1R pathway results in increased tumor cell proliferation and survival. Recent loss-of-function models have shown decreased mammary tum...

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Detalles Bibliográficos
Autores principales: Obr, Alison, Maingrette, Krystopher, Chang, Yun-juan, Bulatowicz, Joseph, Wood, Terri L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209025/
http://dx.doi.org/10.1210/jendso/bvaa046.2328