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OR19-07 Metformin Inhibits Activation of the Melanocortin Receptor 2 and 3 in Vitro, a Possible Mechanism for Its Anti-Androgenic and Weight Balancing Effects in Vivo

Metformin is recommended as one of the first-line drugs for the treatment of type 2 diabetes and the metabolic syndrome. In addition to its insulin sensitizing effects, it has been shown to attenuate androgen excess in women with polycystic ovary syndrome (PCOS) or congenital adrenal hyperplasia (CA...

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Detalles Bibliográficos
Autores principales: Flueck, Christa E, Parween, Shaheena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209312/
http://dx.doi.org/10.1210/jendso/bvaa046.821