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OR19-07 Metformin Inhibits Activation of the Melanocortin Receptor 2 and 3 in Vitro, a Possible Mechanism for Its Anti-Androgenic and Weight Balancing Effects in Vivo
Metformin is recommended as one of the first-line drugs for the treatment of type 2 diabetes and the metabolic syndrome. In addition to its insulin sensitizing effects, it has been shown to attenuate androgen excess in women with polycystic ovary syndrome (PCOS) or congenital adrenal hyperplasia (CA...
Autores principales: | Flueck, Christa E, Parween, Shaheena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209312/ http://dx.doi.org/10.1210/jendso/bvaa046.821 |
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