Characterization of a human monoclonal antibody generated from a B-cell specific for a prefusion-stabilized spike protein of Middle East respiratory syndrome coronavirus

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory infection and continues to infect humans, thereby contributing to a high mortality rate (34.3% in 2019). In the absence of an available licensed vaccine and antiviral agent, therapeutic human antibodies have been sugge...

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Detalles Bibliográficos
Autores principales: Choi, Jang-Hoon, Woo, Hye-Min, Lee, Tae-young, Lee, So-young, Shim, Sang-Mu, Park, Woo-Jung, Yang, Jeong-Sun, Kim, Joo Ae, Yun, Mi-Ran, Kim, Dae-Won, Kim, Sung Soon, Zhang, Yi, Shi, Wei, Wang, Lingshu, Graham, Barney S., Mascola, John R., Wang, Nanshuang, McLellan, Jason S., Lee, Joo-Yeon, Lee, Hansaem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209324/
https://www.ncbi.nlm.nih.gov/pubmed/32384116
http://dx.doi.org/10.1371/journal.pone.0232757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209324/
https://www.ncbi.nlm.nih.gov/pubmed/32384116
http://dx.doi.org/10.1371/journal.pone.0232757

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