Cargando…
Characterization of a human monoclonal antibody generated from a B-cell specific for a prefusion-stabilized spike protein of Middle East respiratory syndrome coronavirus
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory infection and continues to infect humans, thereby contributing to a high mortality rate (34.3% in 2019). In the absence of an available licensed vaccine and antiviral agent, therapeutic human antibodies have been sugge...
Autores principales: | Choi, Jang-Hoon, Woo, Hye-Min, Lee, Tae-young, Lee, So-young, Shim, Sang-Mu, Park, Woo-Jung, Yang, Jeong-Sun, Kim, Joo Ae, Yun, Mi-Ran, Kim, Dae-Won, Kim, Sung Soon, Zhang, Yi, Shi, Wei, Wang, Lingshu, Graham, Barney S., Mascola, John R., Wang, Nanshuang, McLellan, Jason S., Lee, Joo-Yeon, Lee, Hansaem |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209324/ https://www.ncbi.nlm.nih.gov/pubmed/32384116 http://dx.doi.org/10.1371/journal.pone.0232757 |
Ejemplares similares
-
The structure of a novel antibody against the spike protein inhibits Middle East respiratory syndrome coronavirus infections
por: Jang, Tae-Ho, et al.
Publicado: (2022) -
Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation
por: Wrapp, Daniel, et al.
Publicado: (2020) -
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
por: Wrapp, Daniel, et al.
Publicado: (2020) -
The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation
por: Wrapp, Daniel, et al.
Publicado: (2019) -
Selection and Characterization of Monoclonal Antibodies Targeting Middle East Respiratory Syndrome Coronavirus through a Human Synthetic Fab Phage Display Library Panning
por: Kim, Yoonji, et al.
Publicado: (2019)