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The double-edged sword role of fibroblasts in the interaction with cancer cells; an agent-based modeling approach
Fibroblasts as key components of tumor microenvironment show different features in the interaction with cancer cells. Although, Normal fibroblasts demonstrate anti-tumor effects, cancer associated fibroblasts are principal participant in tumor growth and invasion. The ambiguity of fibroblasts functi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209353/ https://www.ncbi.nlm.nih.gov/pubmed/32384110 http://dx.doi.org/10.1371/journal.pone.0232965 |