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SUN-361 Cultured Murine Osteoblasts Convert DHEA to Testosterone

Androgens have complex effects on the skeleton. Besides gonadal testosterone (T), the adrenal produces the androgen precursor dehydroepiandrosterone (DHEA), using 3β- and 17β-hydroxysteroid dehydrogenases (3βHSD & 17βHSD) to convert to T in target tissues. Microarray analyses of murine calvarial...

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Detalles Bibliográficos
Autores principales: Clines, Katrina L, Moon, Henry H, O’Day, Patrick J, Farber, Charles R, Auchus, Richard Joseph, Clines, Gregory A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209491/
http://dx.doi.org/10.1210/jendso/bvaa046.755