SAT-597 Hypothalamic ESR1 Gene Knockdown Elicits Intermittent Decrement in Postprandial Energy Expenditure Associated with Obesity Onset in Female Rhesus Monkeys

Declining serum estradiol (E(2)) levels during the menopausal transition are associated with increased central adiposity and heightened risk for metabolic disease. Estrogenic effects on adiposity and metabolism in female rodents are primarily mediated by estrogen receptor alpha (ESR1) activation in...

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Detalles Bibliográficos
Autores principales: Willging, Molly, Levine, Jon E, Greinwald, Emily, Flowers, Matthew T, Colman, Ricki J, Abbott, David Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Adipose Tissue, Appetite, and Obesity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209601/
http://dx.doi.org/10.1210/jendso/bvaa046.1807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209601/
http://dx.doi.org/10.1210/jendso/bvaa046.1807

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