SAT-031 Linking Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) to Histone Ubiquitination Network and Acetylation During Spermiogenesis

Gonadotropin Regulated Testicular Helicase (GRTH/DDX25), a testis specific RNA helicase essential for the completion of spermatogenesis. Our early studies discovered a missense mutation (R(242)H) of GRTH gene in 5.8 % of a Japanese population with azoospermia. This mutation in COS-1 cells showed los...

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Detalles Bibliográficos
Autores principales: Kavarthapu, Raghuveer, Anbazhagan, Rajakumar, Dufau, Maria L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209657/
http://dx.doi.org/10.1210/jendso/bvaa046.949