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SAT-031 Linking Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) to Histone Ubiquitination Network and Acetylation During Spermiogenesis
Gonadotropin Regulated Testicular Helicase (GRTH/DDX25), a testis specific RNA helicase essential for the completion of spermatogenesis. Our early studies discovered a missense mutation (R(242)H) of GRTH gene in 5.8 % of a Japanese population with azoospermia. This mutation in COS-1 cells showed los...
Autores principales: | Kavarthapu, Raghuveer, Anbazhagan, Rajakumar, Dufau, Maria L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209657/ http://dx.doi.org/10.1210/jendso/bvaa046.949 |
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