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SUN-592 Adipocyte Specific Endothelin a Receptor Knockout Increases Adiposity in Mice
Obesity is associated with increased levels of Endothelin-1 (ET-1). Blockade of ET-1 type A receptors (ET(A)) improves lipid profile in patients with chronic kidney disease; however the mechanism is unknown.[1] In adipocytes ET(A) activation increases lipolysis, a potential mechanism for elevated li...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209660/ http://dx.doi.org/10.1210/jendso/bvaa046.1897 |