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SUN-592 Adipocyte Specific Endothelin a Receptor Knockout Increases Adiposity in Mice

Obesity is associated with increased levels of Endothelin-1 (ET-1). Blockade of ET-1 type A receptors (ET(A)) improves lipid profile in patients with chronic kidney disease; however the mechanism is unknown.[1] In adipocytes ET(A) activation increases lipolysis, a potential mechanism for elevated li...

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Detalles Bibliográficos
Autores principales:	Rivera-Gonzalez, Osvaldo, Speed, Joshua S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Adipose Tissue, Appetite, and Obesity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209660/ http://dx.doi.org/10.1210/jendso/bvaa046.1897

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