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OR24-01 Mutational Study of the GPR119 Receptor Binding Site

The GPR119 receptor, a class A G-protein coupled receptor located in the pancreatic β cells, induces insulin production when activated. Due to its specific activity, the pharmaceutical industry has identified GPR119 as a target for the treatment for type 2 diabetes. The lack of a GRP119 crystal stru...

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Detalles Bibliográficos
Autores principales: Rosales, Matthew D, Dean, Frank, Kotsikorou, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209689/
http://dx.doi.org/10.1210/jendso/bvaa046.1659