OR19-03 Effects of Nonpeptide Orally Bioavailable ACTH Antagonists on Adrenal Gland Size and Function in Rats

Cushing’s disease (CD) and Ectopic ACTH syndrome (EAS) stem from excess circulating adrenocorticotropic hormone (ACTH) and resulting hypercortisolemia. In CD, excess ACTH is secreted from pituitary tumors, whereas excess ACTH in EAS arises from nonpituitary tumors. ACTH acts on the adrenal melanocor...

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Detalles Bibliográficos
Autores principales: Markison, Stacy, Fowler, Melissa A, Athanacio, Jon, Kredel, Taylor A, Antwan, Agnes, Johns, Michael, Tsivkovski, Oleg, Cruz, Shirley, Luo, Rosa, Reinhart, Greg, Kusnetzow, Ana Karin, Madan, Ajay, Betz, Stephen F, Struthers, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209714/
http://dx.doi.org/10.1210/jendso/bvaa046.699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209714/
http://dx.doi.org/10.1210/jendso/bvaa046.699

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