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OR19-03 Effects of Nonpeptide Orally Bioavailable ACTH Antagonists on Adrenal Gland Size and Function in Rats
Cushing’s disease (CD) and Ectopic ACTH syndrome (EAS) stem from excess circulating adrenocorticotropic hormone (ACTH) and resulting hypercortisolemia. In CD, excess ACTH is secreted from pituitary tumors, whereas excess ACTH in EAS arises from nonpituitary tumors. ACTH acts on the adrenal melanocor...
Autores principales: | Markison, Stacy, Fowler, Melissa A, Athanacio, Jon, Kredel, Taylor A, Antwan, Agnes, Johns, Michael, Tsivkovski, Oleg, Cruz, Shirley, Luo, Rosa, Reinhart, Greg, Kusnetzow, Ana Karin, Madan, Ajay, Betz, Stephen F, Struthers, Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209714/ http://dx.doi.org/10.1210/jendso/bvaa046.699 |
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