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Plasma Soluble αKlotho, Serum Fibroblast Growth Factor 23, and Mobility Disability in Community-Dwelling Older Adults

CONTEXT: αKlotho is a hormone and co-receptor for fibroblast growth factor 23 (FGF23), a hormone that downregulates active vitamin D synthesis and promotes phosphate excretion. Low αKlotho and high FGF23 occur in chronic kidney disease (CKD). OBJECTIVE: We aimed to assess the relationships of αKloth...

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Detalles Bibliográficos
Autores principales: Shardell, Michelle, Drew, David A, Semba, Richard D, Harris, Tamara B, Cawthon, Peggy M, Simonsick, Eleanor M, Kalyani, Rita R, Schwartz, Ann V, Kritchevsky, Stephen B, Newman, Anne B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209777/
https://www.ncbi.nlm.nih.gov/pubmed/32405607
http://dx.doi.org/10.1210/jendso/bvz032