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Bioinspired design of a robust d(3)-methylating agent

Methods to incorporate deuterium atoms into organic molecules are valuable for the pharmaceutical industry. The introduction of deuterium atoms by a synthetic method enables the direct tracing of the drug molecule without substantially altering its structure or function. The methyl group is one of t...

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Detalles Bibliográficos
Autores principales: Wang, Minyan, Zhao, Yunfei, Zhao, Yue, Shi, Zhuangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209982/
https://www.ncbi.nlm.nih.gov/pubmed/32426486
http://dx.doi.org/10.1126/sciadv.aba0946