Quinacrine inhibits GSTA1 activity and induces apoptosis through G(1)/S arrest and generation of ROS in human non-small cell lung cancer cell lines

Background: Quinacrine (QC) is popular for its anti-malarial activity. It has been reported exhibiting anti-cancerous properties by suppressing nuclear factor-κB and activating p53 signaling; however, its effect on cellular pathways in human non-small cell lung cancer (NSCLC) has not been studied. M...

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Detalles Bibliográficos
Autores principales: Kumar, Makhan, Martin, Ansie, Nirgude, Snehal, Chaudhary, Bibha, Mondal, Sukanta, Sarkar, Angshuman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210017/
https://www.ncbi.nlm.nih.gov/pubmed/32405336
http://dx.doi.org/10.18632/oncotarget.27558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210017/
https://www.ncbi.nlm.nih.gov/pubmed/32405336
http://dx.doi.org/10.18632/oncotarget.27558

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