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Quinacrine inhibits GSTA1 activity and induces apoptosis through G(1)/S arrest and generation of ROS in human non-small cell lung cancer cell lines
Background: Quinacrine (QC) is popular for its anti-malarial activity. It has been reported exhibiting anti-cancerous properties by suppressing nuclear factor-κB and activating p53 signaling; however, its effect on cellular pathways in human non-small cell lung cancer (NSCLC) has not been studied. M...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210017/ https://www.ncbi.nlm.nih.gov/pubmed/32405336 http://dx.doi.org/10.18632/oncotarget.27558 |