Minicircle DNA-Mediated CAR T Cells Targeting CD44 Suppressed Hepatocellular Carcinoma Both in vitro and in vivo

PURPOSE: Based on the continuous exploration of solid tumor immunotherapy, we focused on hepatocellular carcinoma with a high level of morbidity and mortality. We confirm the stability of mcDNA-based CAR T cell generating platform, and investigate the antitumor activity of CD44-CAR T cells against h...

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Detalles Bibliográficos
Autores principales: Wang, Hezhi, Ye, Xueshuai, Ju, Yi, Cai, Ziqi, Wang, Xiaoxiao, Du, Pingping, Zhang, Mengya, Li, Yang, Cai, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210041/
https://www.ncbi.nlm.nih.gov/pubmed/32440140
http://dx.doi.org/10.2147/OTT.S247836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210041/
https://www.ncbi.nlm.nih.gov/pubmed/32440140
http://dx.doi.org/10.2147/OTT.S247836

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