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Minicircle DNA-Mediated CAR T Cells Targeting CD44 Suppressed Hepatocellular Carcinoma Both in vitro and in vivo

PURPOSE: Based on the continuous exploration of solid tumor immunotherapy, we focused on hepatocellular carcinoma with a high level of morbidity and mortality. We confirm the stability of mcDNA-based CAR T cell generating platform, and investigate the antitumor activity of CD44-CAR T cells against h...

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Detalles Bibliográficos
Autores principales:	Wang, Hezhi, Ye, Xueshuai, Ju, Yi, Cai, Ziqi, Wang, Xiaoxiao, Du, Pingping, Zhang, Mengya, Li, Yang, Cai, Jianhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210041/ https://www.ncbi.nlm.nih.gov/pubmed/32440140 http://dx.doi.org/10.2147/OTT.S247836

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