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Liability threshold modeling of case-control status and family history of disease increases association power
Family history of disease can provide valuable information in case-control association studies, but it is currently unclear how to best combine case-control status and family history of disease. We developed an association method based on posterior mean genetic liabilities under a liability threshol...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210076/ https://www.ncbi.nlm.nih.gov/pubmed/32313248 http://dx.doi.org/10.1038/s41588-020-0613-6 |