NCOA5 deficiency promotes a unique liver protumorigenic microenvironment through p21(WAF1/CIP1) overexpression, which is reversed by metformin

Prevention and treatment options for hepatocellular carcinoma (HCC) are presently limited, underscoring the necessity for further elucidating molecular mechanisms underlying HCC development and identifying new prevention and therapeutic targets. Here, we demonstrate a unique protumorigenic niche in...

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Detalles Bibliográficos
Autores principales: Williams, Mark, Liu, Xinhui, Zhang, Yueqi, Reske, Jake, Bahal, Devika, Gohl, Trevor G., Hollern, Daniel, Ensink, Elliot, Kiupel, Matti, Luo, Rongcheng, Das, Rupali, Xiao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210077/
https://www.ncbi.nlm.nih.gov/pubmed/32203160
http://dx.doi.org/10.1038/s41388-020-1256-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210077/
https://www.ncbi.nlm.nih.gov/pubmed/32203160
http://dx.doi.org/10.1038/s41388-020-1256-x

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