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Differential microRNA expression profiles associated with microsatellite status reveal possible epigenetic regulation of microsatellite instability in gastric adenocarcinoma

BACKGROUND: Although microsatellite instability (MSI) is a powerful predictive biomarker for the efficacy of immunotherapy, the mechanism of MSI in sporadic gastrointestinal cancer is not fully understood. However, epigenetics, particularly microRNAs, has been suggested as one of the main regulators...

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Detalles Bibliográficos
Autores principales: Qu, Xiaofei, Zhao, Liqin, Zhang, Ruoxin, Wei, Qingyi, Wang, Mengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210178/
https://www.ncbi.nlm.nih.gov/pubmed/32395528
http://dx.doi.org/10.21037/atm.2020.03.54