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IntegrinB5 upregulated by HER2 in gastric cancer: a promising biomarker for liver metastasis

BACKGROUND: Liver is the most frequent metastatic site of gastric cancer (GC), especially in patients with HER2 positive GC. Exosomal integrin αvβ5 has been shown to promote liver metastasis (LM), and the cross talk between integrins and HER2 during breast cancer metastasis has been reported. Howeve...

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Detalles Bibliográficos
Autores principales: Li, Qian, Peng, Ke, Chen, Erbao, Jiang, Huiqin, Wang, Yan, Yu, Shan, Li, Wei, Yu, Yiyi, Liu, Tianshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210205/
https://www.ncbi.nlm.nih.gov/pubmed/32395495
http://dx.doi.org/10.21037/atm.2020.03.184