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Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor

A basic question linked to differential patterns of gene expression is how cells reach different fates despite using the same DNA template. Since 5-hydroxymethylcytosine (5hmC) emerged as an intermediate metabolite in active DNA demethylation, there have been increasing efforts to elucidate its func...

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Detalles Bibliográficos
Autores principales: Rodríguez-Aguilera, Jesús Rafael, Ecsedi, Szilvia, Goldsmith, Chloe, Cros, Marie-Pierre, Domínguez-López, Mariana, Guerrero-Celis, Nuria, Pérez-Cabeza de Vaca, Rebeca, Chemin, Isabelle, Recillas-Targa, Félix, Chagoya de Sánchez, Victoria, Hernández-Vargas, Héctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210258/
https://www.ncbi.nlm.nih.gov/pubmed/32385352
http://dx.doi.org/10.1038/s41598-020-64700-2