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Sequential Ras/MAPK and PI3K/AKT/mTOR pathways recruitment drives basal extrusion in the prostate-like gland of Drosophila

One of the most important but less understood step of epithelial tumourigenesis occurs when cells acquire the ability to leave their epithelial compartment. This phenomenon, described as basal epithelial cell extrusion (basal extrusion), represents the first step of tumour invasion. However, due to...

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Detalles Bibliográficos
Autores principales: Rambur, Amandine, Lours-Calet, Corinne, Beaudoin, Claude, Buñay, Julio, Vialat, Marine, Mirouse, Vincent, Trousson, Amalia, Renaud, Yoan, Lobaccaro, Jean-Marc A., Baron, Silvère, Morel, Laurent, de Joussineau, Cyrille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210301/
https://www.ncbi.nlm.nih.gov/pubmed/32385236
http://dx.doi.org/10.1038/s41467-020-16123-w