Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia

An on-demand anesthetic that would only take effect when needed and where the intensity of anesthesia could be easily adjustable according to patients’ needs would be highly desirable. Here, we design and synthesize a macromolecular prodrug (P407-CM-T) in which the local anesthetic tetracaine (T) is...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wei, Ji, Tianjiao, Li, Yang, Zheng, Yueqin, Mehta, Manisha, Zhao, Chao, Liu, Andong, Kohane, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210304/
https://www.ncbi.nlm.nih.gov/pubmed/32385252
http://dx.doi.org/10.1038/s41467-020-16177-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210304/
https://www.ncbi.nlm.nih.gov/pubmed/32385252
http://dx.doi.org/10.1038/s41467-020-16177-w

Ejemplares similares