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Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia
An on-demand anesthetic that would only take effect when needed and where the intensity of anesthesia could be easily adjustable according to patients’ needs would be highly desirable. Here, we design and synthesize a macromolecular prodrug (P407-CM-T) in which the local anesthetic tetracaine (T) is...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210304/ https://www.ncbi.nlm.nih.gov/pubmed/32385252 http://dx.doi.org/10.1038/s41467-020-16177-w |