Rational Design of an Activatable Reporter for Quantitative Imaging of RNA Aberrant Splicing In Vivo

Pre-mRNA splicing, the process of removing introns from pre-mRNA and the arrangement of exons to produce mature transcripts, is a crucial step in the expression of most eukaryote genes. However, the splicing kinetics remain poorly characterized in living cells, mainly because current methods cannot...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Jinrong, Zheng, Haifeng, Chen, Si, Shi, Xiaorui, Mao, Wenjie, Wang, Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210378/
https://www.ncbi.nlm.nih.gov/pubmed/32405512
http://dx.doi.org/10.1016/j.omtm.2020.04.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210378/
https://www.ncbi.nlm.nih.gov/pubmed/32405512
http://dx.doi.org/10.1016/j.omtm.2020.04.007

Ejemplares similares