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Rational Design of an Activatable Reporter for Quantitative Imaging of RNA Aberrant Splicing In Vivo
Pre-mRNA splicing, the process of removing introns from pre-mRNA and the arrangement of exons to produce mature transcripts, is a crucial step in the expression of most eukaryote genes. However, the splicing kinetics remain poorly characterized in living cells, mainly because current methods cannot...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210378/ https://www.ncbi.nlm.nih.gov/pubmed/32405512 http://dx.doi.org/10.1016/j.omtm.2020.04.007 |