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In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2

Successful in situ therapeutic vaccination would allow locally delivered oncolytic virus (OV) to exert systemic immunologic effects on metastases and improve survival. We have utilized bilateral flank tumor models to determine the most efficacious regimens of in situ vaccination. Intratumoral inject...

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Detalles Bibliográficos
Autores principales: Liu, Weilin, Dai, Enyong, Liu, Zuqiang, Ma, Congrong, Guo, Zong Sheng, Bartlett, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210382/
https://www.ncbi.nlm.nih.gov/pubmed/32405533
http://dx.doi.org/10.1016/j.omto.2020.04.006