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G Protein-Coupled Receptor GPR87 Promotes the Expansion of PDA Stem Cells through Activating JAK2/STAT3

Cancer stem cells are the main reason for drug resistance and tumor relapse, and screening the targets for cancer stem cells is essential for tumor therapy. Here, we studied the role and regulatory mechanism of a G protein-coupled receptor named as G protein-coupled receptor 87 (GPR87) in the expans...

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Detalles Bibliográficos
Autores principales: Jiang, Jianxin, Yu, Chao, Guo, Xingjun, Zhang, Hao, Tian, She, Cai, Kun, He, Zhiwei, Sun, Chengyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210383/
https://www.ncbi.nlm.nih.gov/pubmed/32405536
http://dx.doi.org/10.1016/j.omto.2020.01.006