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GPR50 Promotes Hepatocellular Carcinoma Progression via the Notch Signaling Pathway through Direct Interaction with ADAM17

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, and it is thus critical to identify novel molecular biomarkers of HCC prognosis and elucidate the molecular mechanisms underlying HCC progression. Here, we show that G-protein-coupled receptor 50 (GPR50) in HCC is o...

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Detalles Bibliográficos
Autores principales: Saha, Subbroto Kumar, Choi, Hye Yeon, Yang, Gwang-Mo, Biswas, Polash Kumar, Kim, Kyeongseok, Kang, Geun-Ho, Gil, Minchan, Cho, Ssang-Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210388/
https://www.ncbi.nlm.nih.gov/pubmed/32405532
http://dx.doi.org/10.1016/j.omto.2020.04.002